The earliest known form of toothpaste was discovered in Egypt around the 4th century AD. The toothpaste contains salt, Pepper Includes plantain, and iris flowers. The Romans developed toothpaste based on human urine. In the 9th century, Ziryab, a Persian musician and fashion designer, invented toothpaste. The toothpaste became popular among Islamic Spaniards. The exact composition of the toothpaste is not known, but it is said to be not only useful but also fragrant.